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SHP099

SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM) . SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.

Product Specifications

CAS Number

1801747-42-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

352.26

Molecular Formula

C16H19Cl2N5

Notes

Research use only, not for human use.

Receptor

Antifungal

Available Sizes

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