GDC0575 monohydrochloride
GDC-0575 is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.
Product Specifications
CAS Number
1196504-54-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
414.73
Molecular Formula
C16H21BrClN5O
Notes
Research use only, not for human use.
Receptor
HSGLT2
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
RZB30774-01 50 mg
1-{[5-Chloro-2- (difluoromethoxy) phenyl]methyl}-5-nitro-1,2-dihydropyridin-2-one
Sign In for Pricing
View Details RZB30774-02 0.5 g
1-{[5-Chloro-2- (difluoromethoxy) phenyl]methyl}-5-nitro-1,2-dihydropyridin-2-one
Sign In for Pricing
View Details