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NB-360

NB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cathepsin E, and cathepsin D.

Product Specifications

CAS Number

1262857-73-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

449.41

Molecular Formula

C21H19F4N5O2

Notes

Research use only, not for human use.

Receptor

Lp-PLA2

Available Sizes

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