NB-360
NB-360 is a potent and brain-penetrable inhibitor of BACE1 and BACE2 with IC50s of 5, 5, and 6 nM for mouse and human BACE1 and BACE2. NB-360 exhibits excellent selectivity over the related aspartyl proteases pepsin, cathepsin E, and cathepsin D.
Product Specifications
CAS Number
1262857-73-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
449.41
Molecular Formula
C21H19F4N5O2
Notes
Research use only, not for human use.
Receptor
Lp-PLA2
Available Sizes
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