HKI-357
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM) . HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.
Product Specifications
CAS Number
848133-17-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
574.05
Molecular Formula
C31H29ClFN5O3
Notes
Research use only, not for human use.
Receptor
PEGs
Available Sizes
Frequently Asked Questions
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