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HKI-357

HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM) . HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.

Product Specifications

CAS Number

848133-17-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

574.05

Molecular Formula

C31H29ClFN5O3

Notes

Research use only, not for human use.

Receptor

PEGs

Available Sizes

Frequently Asked Questions

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