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F-1

F-1 is IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways.

Product Specifications

CAS Number

2244775-31-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

519.02

Molecular Formula

C22H27ClN8O3S

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

Frequently Asked Questions

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