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PIN1 inhibitor API-1

PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM) . PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development.

Product Specifications

CAS Number

680622-70-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

366.3

Molecular Formula

C15H13F3N6O2

Notes

Research use only, not for human use.

Receptor

Pin1

Available Sizes

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