PIN1 inhibitor API-1
PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM) . PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development.
Product Specifications
CAS Number
680622-70-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
366.3
Molecular Formula
C15H13F3N6O2
Notes
Research use only, not for human use.
Receptor
Pin1
Available Sizes
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