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PD146176

PD146176 is an inhibitor of 15-Lipoxygenase (15-LO), it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.

Product Specifications

CAS Number

4079-26-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

237.32

Molecular Formula

C15H11NS

Notes

Research use only, not for human use.

Receptor

15-LO|Autophagy

Available Sizes

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