PD146176
PD146176 is an inhibitor of 15-Lipoxygenase (15-LO), it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.
Product Specifications
CAS Number
4079-26-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
237.32
Molecular Formula
C15H11NS
Notes
Research use only, not for human use.
Receptor
15-LO|Autophagy
Available Sizes
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