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BSJ-4-116

BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly (adenylation) .

Product Specifications

CAS Number

2519823-34-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

837.38

Molecular Formula

C40H49ClN8O8S

Notes

Research use only, not for human use.

Receptor

CDK12|Cereblon

Available Sizes

Curated Selection

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