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Lifirafenib

Lifirafenib is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively.

Product Specifications

CAS Number

1446090-79-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

478.42

Molecular Formula

C25H17F3N4O3

Notes

Research use only, not for human use.

Receptor

B-Raf (V600E) |EGFR|EGFR (L858R/T790M)

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