Lifirafenib
Lifirafenib is a potent inhibitor of RAF family kinases and EGFR in biochemical assays with IC50 of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant respectively.
Product Specifications
CAS Number
1446090-79-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
478.42
Molecular Formula
C25H17F3N4O3
Notes
Research use only, not for human use.
Receptor
B-Raf (V600E) |EGFR|EGFR (L858R/T790M)
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