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Isosilybin A

Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostate cancer (PCA) activity that is mediated via cell cycle arrest and apoptosis induction.

Product Specifications

CAS Number

142796-21-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

482.44

Molecular Formula

C25H22O10

Notes

Research use only, not for human use.

Receptor

ABCA1|PPARγ|Tyrosinase

Available Sizes

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