Capmatinib hydrochloride
Capmatinib hydrochloride is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR) with potential antineoplastic activity.Capmatinib was found to be highly selective for MET over other kinases. It was active against cancer models that are characterized by MET amplification, marked MET overexpression, MET exon 14 skipping mutations, or MET activation via expression of the ligand hepatocyte growth factor (HGF) .
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
503.4
Molecular Formula
C23H21Cl2FN6O2
Notes
Research use only, not for human use.
Receptor
C-Met
CAS Number
1865733-40-9
Available Sizes
Curated Selection
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