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Capmatinib hydrochloride

Capmatinib hydrochloride is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR) with potential antineoplastic activity.Capmatinib was found to be highly selective for MET over other kinases. It was active against cancer models that are characterized by MET amplification, marked MET overexpression, MET exon 14 skipping mutations, or MET activation via expression of the ligand hepatocyte growth factor (HGF) .

Product Specifications

CAS Number

1865733-40-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

503.4

Molecular Formula

C23H21Cl2FN6O2

Notes

Research use only, not for human use.

Receptor

C-Met

Available Sizes

Curated Selection

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