Gap19 acetate (1507930-57-5, free)
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.Hemichannel inhibition is due to the binding of Gap19 to the C-terminus (CT) thereby preventing intramolecular CT-CL interactions. The peptide inhibited Cx43 hemichannel unitary currents in both HeLa cells exogenously expressing Cx43 and acutely isolated pig ventricular cardiomyocytes.
Product Specifications
CAS Number
1507930-57-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1161.44
Molecular Formula
C55H96N14O13
Notes
Research use only, not for human use.
Receptor
Cx43
Available Sizes
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