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KGA-2727

KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat) . KGA-2727 for the treatment of diabete.KGA-2727, which has a pyrazole-O-glucoside structure, as the first selective SGLT1 inhibitor.

Product Specifications

CAS Number

666842-36-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

536.62

Molecular Formula

C26H40N4O8

Notes

Research use only, not for human use.

Receptor

SGLT1

Available Sizes

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