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Resatorvid

Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4) . Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM) .Resatorvid suppresses the production of NO, TNF-α, and IL-6 from LPS-stimulated human peripheral blood mononuclear cells (PBMCs, IC50s: 11-33 nM) .

Product Specifications

CAS Number

243984-11-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

361.82

Molecular Formula

C15H17ClFNO4S

Notes

Research use only, not for human use.

Receptor

TLR4|TNF-R

Available Sizes

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