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NLX-204 hydrochloride (2170405-10-2 free base)

NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist (pKi = 10.19) .NLX-204, displayed high selectivity in the SafetyScreen44 panel (including hERG channel), high solubility, metabolic stability, and Caco-2 penetration and did not block CYP3A4, CYP2D6 isoenzymes, or P-glycoprotein.

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

409.13

Molecular Formula

C20H23Cl2F2N3O2

Notes

Research use only, not for human use.

Receptor

5-HT1A

Available Sizes

Curated Selection

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