Pyr6
Pyr6 is a selective TRPC3 inhibitor with IC50 of 0.49 uM (Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells) .Pyr6 is an inhibitor of Ca2+ entry, which displays higher potency to inhibit Ca2+ entry mediated by CRAC channel than by TRPC3.Pyr3 is selective inhibitor of TRPC3, inhibited Orai1- and TRPC3-mediated Ca (2+) entry and currents as well as mast cell activation with similar potency.
Product Specifications
CAS Number
245747-08-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
418.27
Molecular Formula
C17H9F7N4O
Notes
Research use only, not for human use.
Receptor
TRPC3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
