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Trilaciclib hydrochloride

Trilaciclib hydrochloride is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6) .Incubation with Trilaciclib hydrochloride (G1T28) for 24 hours can induce a strong G1 cell cycle arrest (time=0) . Cells have re-entered the cell cycle and demonstrate cell-cycle kinetics similar to untreated control cells By 16 hours after Trilaciclib hydrochloride washout.

Product Specifications

CAS Number

1977495-97-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

519.47

Molecular Formula

C24H32Cl2N8O

Notes

Research use only, not for human use.

Receptor

Cdk4/cyclin D1|cdk6/cyclin D3

Available Sizes

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