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AMG 487

AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively.

Product Specifications

CAS Number

473719-41-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

603.59

Molecular Formula

C32H28F3N5O4

Notes

Research use only, not for human use.

Receptor

CXCR3

Available Sizes

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