AMG 487
AMG 487 prevents the chemokines I-IP-10 and I-ITAC from binding to CXCR3. In the cellular assays, AMG 487 inhibits CXCR3-mediated cell migration with IC50 values of 8nM, 15nM and 36nM for I-IP-10, I-ITAC and MIG, respectively.
Product Specifications
CAS Number
473719-41-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
603.59
Molecular Formula
C32H28F3N5O4
Notes
Research use only, not for human use.
Receptor
CXCR3
Available Sizes
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