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MLN120B

MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM) .MLN120B almost completely blocks the stimulation of MM.1S, U266, and INA6 cell growth, as well as IL-6 secretion from BMSCs, induced by multiple myeloma cell adherence to BMSCs [1]. MLN120B shows an inhibitory effect on LPS induced NF-κB activation in RAW267.4 cells.

Product Specifications

CAS Number

783348-36-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

366.8

Molecular Formula

C19H15ClN4O2

Notes

Research use only, not for human use.

Receptor

IKKβ

Available Sizes

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