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N-Nornuciferine hydrochloride

N-Nornuciferine is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM) .N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9) . N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan O-demethylation (Ki: 2.34 μM) .

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

——

Molecular Formula

——

Notes

Research use only, not for human use.

Receptor

CYP2D6

Available Sizes

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