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NNMTi

NNMTi is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathwayNNMTi treatment will rescue age-related deficits in muSC activity to promote superior regeneration post-injury in aging muscle.

Product Specifications

CAS Number

42464-96-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

286.11

Molecular Formula

C10H11IN2

Notes

Research use only, not for human use.

Receptor

NNMT

Available Sizes

Curated Selection

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