NNMTi
NNMTi is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adipocytes 1-methylnicotinamide level (EC50 = 2.3 μM) without affecting related methyltransferases & enzymes in the NAD+ salvage pathwayNNMTi treatment will rescue age-related deficits in muSC activity to promote superior regeneration post-injury in aging muscle.
Product Specifications
CAS Number
42464-96-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
286.11
Molecular Formula
C10H11IN2
Notes
Research use only, not for human use.
Receptor
NNMT
Available Sizes
Curated Selection
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