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Retigabine dihydrochloride

Retigabine dihydrochloride is an anticonvulsant used as an adjunctive treatment for partial epilepsies in treatment-experienced adult patients. The mechanism of action involves opening of neuronal K (V) 7.2-7.5 (formerly KCNQ2-5) voltage-activated K (+) channels.In differentiated PC12 cells, retigabine enhanced a linopirdine-sensitive current.

Product Specifications

CAS Number

150812-13-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

376.25

Molecular Formula

C16H20Cl2FN3O2

Notes

Research use only, not for human use.

Receptor

KCNQ3/5|KCNQ2/Q3|KCQN4

Available Sizes

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