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APTO-253

APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.APTO-253 (5 μM) induces KLF4 expression and enhances apoptosis induced by NSC 119875 in both SKOV3 and OVCAR3 cells.

Product Specifications

CAS Number

916151-99-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

367.38

Molecular Formula

C22H14FN5

Notes

Research use only, not for human use.

Receptor

C-Myc

Available Sizes

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