APTO-253
APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.APTO-253 (5 μM) induces KLF4 expression and enhances apoptosis induced by NSC 119875 in both SKOV3 and OVCAR3 cells.
Product Specifications
CAS Number
916151-99-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
367.38
Molecular Formula
C22H14FN5
Notes
Research use only, not for human use.
Receptor
C-Myc
Available Sizes
Curated Selection
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