EGFR-IN-7

EGFR-IN-7 is a selective and potent EGFR kinase inhibitor.TQB3804 displayed potent enzymatic activities for EGFRd746-750/T790M/C797S, EGFRL858R/T790M/C797S, EGFRd746-750/T790M, and EGFRL858R/T790M with IC50 of 0.46, 0.13, 0.26, and 0.19 nM respectively, and has similar enzymatic activity for EGFRWT (IC50 = 1.07) to Osimertinib.

Product Specifications

CAS Number

2267329-76-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

694.6

Molecular Formula

C32H41BrN9O2P

Notes

Research use only, not for human use.

Receptor

EGFR

Available Sizes

Curated Selection

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