9-ING-41
9-ING-41 is a glycogen synthase kinase-3 inhibitor.9-ING-41 (2, 4 μM; 48 hours) decreases neuroblastoma cell viability induces apoptosis[2]. 9-ING-41 (0.1-1 µM) inhibits GSK-3 leading to a decreased expression of the NF-κB target XIAP and significant apoptosis in neuroblastoma cells as shown by PARP cleavage, an apoptosis marker[1]. 9-ING-41 (0.5, 1.0, 1.5, 2.0 μM) inhibits the proliferation rate of all TCL and MCL lines with concentrations as low as 1.0 mM.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
404.35
Molecular Formula
C22H13FN2O5
Notes
Research use only, not for human use.
Receptor
GSK-3β
CAS Number
1034895-42-5
Available Sizes
Curated Selection
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