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7α,25-Dihydroxycholesterol

7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183) . 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells[1][2], and it is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM) .

Product Specifications

CAS Number

64907-22-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

418.65

Molecular Formula

C27H46O3

Notes

Research use only, not for human use.

Receptor

Human Endogenous Metabolite|GPR183

Available Sizes

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