BAY-985
BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.BAY-985 inhibits FLT3, RSK4, DRAK1, and ULK1 (IC50s: 123, 276, 311, and 7930 nM) . BAY-985 inhibits the cellular phosphorylation of interferon regulatory factor 3 (IRF3, IC50: 74 nM) .
Product Specifications
CAS Number
2409479-29-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
553.58
Molecular Formula
C27H30F3N9O
Notes
Research use only, not for human use.
Receptor
TBK1|TBK1|IKKε
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