FG 7142
FG 7142 also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM) . FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM) .
Product Specifications
CAS Number
78538-74-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
225.25
Molecular Formula
C13H11N3O
Notes
Research use only, not for human use.
Receptor
GABAA receptor
Available Sizes
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