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Exatecan Mesylate

Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL) .Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.

Product Specifications

CAS Number

169869-90-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

531.55

Molecular Formula

C25H26FN3O7S

Notes

Research use only, not for human use.

Receptor

Topo I

Available Sizes

Frequently Asked Questions

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