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L524-0366

L524-0366 is a TWEAK-Fn14 signaling cascade inhibitor.L524-0366 mitigated maladaptive remodeling with TAC. TWEAK induced secretion of the pro-inflammatory chemokine, monocyte chemoattractant protein 1 from WT but not Fn14-/- fibroblasts in vitro, in part through activation of non-canonical NF-κB signaling.

Product Specifications

CAS Number

951612-19-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

308.79

Molecular Formula

C13H13ClN4OS

Notes

Research use only, not for human use.

Receptor

Fn14

Available Sizes

Frequently Asked Questions

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