L524-0366
L524-0366 is a TWEAK-Fn14 signaling cascade inhibitor.L524-0366 mitigated maladaptive remodeling with TAC. TWEAK induced secretion of the pro-inflammatory chemokine, monocyte chemoattractant protein 1 from WT but not Fn14-/- fibroblasts in vitro, in part through activation of non-canonical NF-κB signaling.
Product Specifications
CAS Number
951612-19-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
308.79
Molecular Formula
C13H13ClN4OS
Notes
Research use only, not for human use.
Receptor
Fn14
Available Sizes
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