EIPA
EIPA (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM) . It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.It is found that EIPA, benzamil, and phenamil rapidly and reversibly block Ca2+-activated TRPP3 channel activation at -50 mV, with IC50s of 143, 10.5, 1.1, and 0.14 μM, respectively.
Product Specifications
CAS Number
1154-25-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
299.76
Molecular Formula
C11H18ClN7O
Notes
Research use only, not for human use.
Receptor
TRPP3 channel| Na+/H+-exchanger (NHE)
Available Sizes
Frequently Asked Questions
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