AV-412

AV-412 is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM) .In cells, MP-412 inhibited autophosphorylation of EGFR and ErbB2 with IC (50) of 43 and 282 nM, respectively.

Product Specifications

CAS Number

451493-31-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

851.41

Molecular Formula

C41H44ClFN6O7S2

Notes

Research use only, not for human use.

Receptor

EGFR|EGFR (L858R) |EGFR (T790M) |EGFR (L858R/T790M) |ErbB2

Available Sizes

Curated Selection

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