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ML382

ML382 is a potent and selective MrgX1 positive allosteric modulator (EC50 : 190 nM) .ML382 enhances the ability of BAM8-22 to inhibit high-voltage-activated Ca2+ channels and attenuate spinal nociceptive transmission, both BAM8-22 and ML382 effectively attenuated evoked, persistent, and spontaneous pain without causing obvious side effects.

Product Specifications

CAS Number

1646499-97-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

360.42

Molecular Formula

C₁₅H₁₁NO₃

Notes

Research use only, not for human use.

Receptor

MrgX1

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