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KIRA6

KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 µM) . It can trigger an apoptotic response.KIRA6 (10-1000 nM, 72 hours) strongly compromises the viability of the KIT-dependent cell line HMC-1.1 at the low nM concentration, in a manner that coincided with KIT blockade.

Product Specifications

CAS Number

1589527-65-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

518.53

Molecular Formula

C28H25F3N6O

Notes

Research use only, not for human use.

Receptor

IRE1α

Available Sizes

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