KIRA6
KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 µM) . It can trigger an apoptotic response.KIRA6 (10-1000 nM, 72 hours) strongly compromises the viability of the KIT-dependent cell line HMC-1.1 at the low nM concentration, in a manner that coincided with KIT blockade.
Product Specifications
CAS Number
1589527-65-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
518.53
Molecular Formula
C28H25F3N6O
Notes
Research use only, not for human use.
Receptor
IRE1α
Available Sizes
Curated Selection
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