MSA-2
MSA-2, a potent and orally available non-nucleotide STING agonist, has EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models.
Product Specifications
CAS Number
129425-81-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
294.32
Molecular Formula
O=C (C1=CC (C (S1) =C2) =CC (OC) =C2OC) CCC (O) =O
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
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