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MSA-2

MSA-2, a potent and orally available non-nucleotide STING agonist, has EC50s of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models.

Product Specifications

CAS Number

129425-81-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

294.32

Molecular Formula

O=C (C1=CC (C (S1) =C2) =CC (OC) =C2OC) CCC (O) =O

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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