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4-Nitro-3- (trifluoromethyl) phenol

4-Nitro-3- (trifluoromethyl) phenol (TFM) is a piscicide that is toxic to lampreys (P. marinus) (LC50 values are 1.97-2.11 for cysts, 2.05-2.21 for fry, 1.6-2.45 for juveniles, and 1.6-1.63 for adults, respectively) . 4-Nitro-3- (trifluoromethyl) phenol is also toxic to juvenile lake sturgeons (A. fulvescens) less than 100 mm, but is nontoxic to a variety of other fish species. 4-Nitro-3- (trifluoromethyl) phenol (50 μM) dissociates oxidative phosphorylation by 22% and 28% in isolated livers of lampreys and rainbow trout (O. mykiss), respectively. 4-Nitro-3- (trifluoromethyl) phenol can be used to control lamprey larval populations.

Product Specifications

CAS Number

[88-30-2]

Product Name Alternative

3- (Trifluoromethyl) -4-Nitrophenol; TFM

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H315, H319, H335

Target

Cytochrome P450; Insecticide

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/4-nitro-3-trifluoromethyl-phenol.html

Purity

99.91

Smiles

OC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1

Molecular Formula

C7H4F3NO3

Molecular Weight

207.11

Precautions

H302+H312+H332, H315, H319, H335

References & Citations

[1]Boogaard, et al. Acute toxicity of TFM and a TFM/niclosamide mixture to selected species of fish, including lake sturgeon (Acipenser fulvescens) and mudpuppies (Necturus maculosus), in laboratory and field exposures. J. Great Lakes Res. 29 (Suppl 1), 529-541 (2003) .

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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