Nicotine Ditartrate

(−) -Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. (−) - (S) -Nicotine is significantly more active at binding nAChRs compared to the (+) - (R) antipode thus nicotine is typically synthesized as (−) - (S) -nicotine with only 0.2-1% of the (+) - (R) isomer present.