Hexamethylene amiloride
HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM) . It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-2.4 µM for various NHE isoforms.
Product Specifications
CAS Number
1428-95-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
311.77
Molecular Formula
C12H18ClN7O
Notes
Research use only, not for human use.
Receptor
NHE exchangers| TRPA1| ASIC3| P2X7
Available Sizes
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