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Hexamethylene amiloride

HMA is an amiloride derivative, shown to inhibit TRPA1-mediated calcium signal (IC50: 35 µM) . It is an inhibitor of the Na+/H+ exchanger (NHE), with Ki of 0.013-2.4 µM for various NHE isoforms.

Product Specifications

CAS Number

1428-95-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

311.77

Molecular Formula

C12H18ClN7O

Notes

Research use only, not for human use.

Receptor

NHE exchangers| TRPA1| ASIC3| P2X7

Available Sizes

Frequently Asked Questions

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